Chrome also has a compatability problem with Flash player, in that the keyboard layout switches back to US English, no matter what it has been set to in the operating system (under Windows XP).
This can be annoying when trying to type email addresses into a Flash form in Chrome using the proper UK English keyboard layout, and even more annoying for other languages.
I did like the layout of Chrome, but now that FF4 has a similar layout, I'm happy.